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Compound: Tesamorelin (Modified GHRH 1–44)
Amount: 10mg per vial
Format: Lyophilized Powder
Chemical Classification: Synthetic 44-Residue GHRH Analog
Research Category: Growth Hormone-Releasing Hormone Receptor (GHRHR)
Chemical Profile: Tesamorelin is a synthetic analog of the 44-residue human growth hormone-releasing hormone sequence. It contains an N-terminal trans-3-hexenoyl modification. Researchers investigate its peptide structure and interactions with the GHRH receptor in laboratory systems.
Research Use Only. Not for human or veterinary use.
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Tesamorelin is a synthetic growth hormone-releasing hormone analog containing 44 amino-acid residues. A trans-3-hexenoyl group modifies the peptide’s N-terminus.
The compound is studied in the GHRH receptor family and in comparisons of modified peptide structures. Its sequence length differs from the shorter GHRH(1–29) peptide known as sermorelin.
| Specification | Details |
|---|---|
| Compound | Tesamorelin (Modified GHRH 1–44) |
| Synonyms | Modified GHRH(1–44) |
| Classification | Synthetic Acylated GHRH Analog |
| Length | 44 Amino Acids |
| Sequence | trans-3-hexenoyl-GHRH(1–44)-NH2 |
| Molecular Formula | C221H366N72O67S |
| Molecular Weight | Approximately 5,136 g/mol |
| CAS Number | 218949-48-5 |
| Form | Lyophilized Powder |
| Amount | 10mg per vial |
| Intended Use | Laboratory Research Only |
trans-3-hexenoyl-YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL-NH2
Tesamorelin is a 44-residue GHRH analog with an N-terminal hexenoyl group. Sermorelin corresponds to an amidated 29-residue N-terminal GHRH fragment. Their sequence lengths and chemical modifications distinguish the two peptides.
Tesamorelin is a peptide ligand associated with the growth hormone-releasing hormone receptor (GHRHR). Scientists examine how GHRH-related molecules interact with this receptor. Comparative receptor research considers the peptide identity and assay environment.
The native GHRH sequence contains 44 amino-acid residues. Tesamorelin retains the GHRH-related chain and adds an N-terminal modification. This structural design is relevant to studies of peptide chemistry and sequence recognition.
The trans-3-hexenoyl group is a defining part of Tesamorelin’s identity. Researchers characterize this modification when comparing peptide analogs. The same GHRH sequence with and without an appended chemical group represents a different molecular preparation.
Sermorelin and Modified GRF(1–29) are shorter GHRH-related peptides. Researchers compare these compounds with longer GHRH sequences to characterize differences in structure and receptor interactions. Sequence length and terminal chemistry matter to each comparison.
GHRHR is a G-protein-coupled receptor associated with intracellular second-messenger signaling. In experimental systems, researchers measure binding and signaling responses to GHRH-related ligands. These assays provide mechanistic information about the tested molecular forms.
Certificates of Analysis (COAs) are posted on the product page when available. To request documentation for a specific lot, contact the Genoscience team with the lot number.
Store unopened lyophilized research material at −20 °C in a dry environment, protected from light and moisture. Allow the sealed vial to reach room temperature before opening to reduce condensation.
Handle using suitable laboratory protective equipment and standard research-facility procedures.
Research Use Only: This product is intended strictly for laboratory research and development.
Not for Human or Veterinary Use: Not intended for human consumption, administration or veterinary applications.
Not an Approved Medicine: This material is not marketed as an FDA-approved drug or treatment.
Research Limitations: Laboratory and preclinical findings do not establish clinical safety or efficacy for this product.
Tesamorelin is a modified 44-residue GHRH analog with an N-terminal hexenoyl group.
It is a 44-residue GHRH-related peptide with a trans-3-hexenoyl N-terminal modification.
Tesamorelin contains 44 residues and a chemical N-terminal modification. Sermorelin is the amidated 29-residue GHRH fragment.
Tesamorelin is associated with GHRHR. Ipamorelin is associated with the growth hormone secretagogue receptor GHSR-1a.
Genoscience lists 10mg of lyophilized Tesamorelin per research vial.
When available, the COA for Tesamorelin 10mg can be found on the product page. You may also contact Genoscience to request a COA for a specific lot.
No. Genoscience sells Tesamorelin 10mg strictly for laboratory research purposes. It is not intended for human or veterinary use.
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Products are not for human or veterinary use, not for use in diagnostic procedures, and have not been evaluated by the U.S. Food and Drug Administration.