SNAP-8 10mg

Original price was: $50.00.Current price is: $30.00.

One vial 10 mg is only $30 for a limited time.

Compound: SNAP-8 (Acetyl Octapeptide-3)
Concentration: 10mg per vial
Format: Lyophilized Powder
Chemical Classification: Synthetic Acetylated Octapeptide / SNAP-25 Mimetic

Chemical Profile: SNAP-8, also known as Acetyl Octapeptide-3, is a synthetic eight-residue peptide modeled on a sequence associated with the N-terminal region of SNAP-25, a protein involved in assembly of the SNARE complex. SNAP-8 incorporates both N-terminal acetylation and C-terminal amidation and has been investigated in controlled biochemical systems for its ability to interact with mechanisms governing SNARE-complex formation and vesicle-mediated exocytosis. Its defined peptide sequence makes it a useful molecular probe for studying protein-protein interactions, membrane-fusion pathways, neurotransmitter-vesicle dynamics, and SNAP-25-associated signaling in experimental models.

  • Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂
  • Mechanism: SNAP-25 mimetic investigated for modulation of SNARE-complex assembly and vesicle-fusion pathways
  • Molecular Weight: ~1,075.2 g/mol

 

Description

Research Applications & Mechanisms:

  1. SNARE Complex Assembly & Protein Interactions
    SNAP-8 is investigated in biochemical models involving the SNARE protein complex, a molecular machinery involved in membrane-vesicle docking and fusion. Because the peptide is modeled on a SNAP-25-associated sequence, researchers can use it to examine competitive protein interactions, complex stability, and changes in SNARE-assembly kinetics under controlled experimental conditions.
  2. Vesicle Fusion & Exocytosis Research
    The SNARE complex plays a central role in regulated exocytosis by facilitating fusion between intracellular vesicles and target membranes. SNAP-8 provides a synthetic molecular probe for studying vesicle-docking efficiency, membrane-fusion dynamics, and the molecular events that precede release of vesicular contents in isolated cellular systems.
  3. SNAP-25-Associated Signaling Models
    SNAP-25 is an integral component of cellular vesicle-release machinery. Laboratory models utilizing SNAP-8 may examine how peptide analogs influence SNAP-25-dependent molecular interactions, associated signaling proteins, and downstream biochemical responses linked to regulated secretion.
  4. Neurotransmitter-Release Pathway Research
    Controlled neuronal and cell-based assays may incorporate SNAP-8 when investigating molecular mechanisms involved in regulated neurotransmitter-vesicle release. Research can focus on changes in vesicle docking, SNARE-complex formation, exocytotic activity, and related intracellular signaling without extending findings beyond the experimental system.
  5. Structure-Activity Comparisons of Synthetic Peptides
    SNAP-8 is structurally related to shorter SNAP-25-derived synthetic peptides such as Acetyl Hexapeptide-8. Comparative assays can evaluate how peptide length, terminal modifications, amino-acid composition, and sequence extension influence biochemical stability, SNARE-associated interactions, and molecular activity in controlled systems.

Important Notices:

  • Research Use Only: This product is sold strictly for scientific research, analytical testing, and laboratory development purposes.
  • Handling: The product is supplied as a lyophilized powder and should be handled using appropriate laboratory protocols for peptide stability, solubility, contamination control, and analytical preparation.
  • Visuals: Vial appearance and cap color may vary from product photos; the label quantity refers to the total active content inside the vial.

Important Legal & Safety Notice: All compounds discussed are intended for in-vitro research and analytical use only. They are not approved for human or animal consumption. Researchers are solely responsible for ensuring their handling, reconstitution, and storage protocols meet all applicable institutional, ethical, and legal standards.

 

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