One bottle 60 units was $350 now $220
Compound: SLU-PP-332
Amount: 5mg per unit; 60 units per bottle (300mg total)
Format: Research Compound in Individually Measured Units
Chemical Classification: Synthetic Small-Molecule ERR Agonist (Not a Peptide)
Research Targets: Estrogen-Related Receptors ERRα, ERRβ and ERRγ
Chemical Profile: SLU-PP-332 is a synthetic, non-peptide research compound described in the scientific literature as a pan-agonist of estrogen-related receptors (ERRs), with notable activity at ERRα. It is studied in nuclear-receptor pharmacology, transcriptional regulation and mitochondrial research. The receptor name refers to the estrogen-related receptor family, which is distinct from classical estrogen receptors.
Research Use Only. Not for human or veterinary use.
Monthly subscription One bottle 60 units was $350 now $220
SLU-PP-332 is a synthetic small molecule, not a peptide. It was developed as a laboratory research tool for investigating the estrogen-related receptor family, commonly abbreviated ERR. This receptor family includes ERRα, ERRβ and ERRγ.
Although these proteins have a name similar to estrogen receptors, ERRs are classified as orphan nuclear receptors and have different functional roles from the classical estrogen receptor system. They are involved in transcriptional regulation of genes associated with cellular metabolism and mitochondrial activity.
SLU-PP-332 is described as a pan-ERR agonist because it exhibits activity at all three ERR subtypes in experimental systems. Published research has reported stronger potency at ERRα than at the other two subtypes.
| Specification | Details |
|---|---|
| Compound | SLU-PP-332 |
| CAS Number | 303760-60-3 |
| Classification | Synthetic Small-Molecule Research Compound |
| Receptor Family | Estrogen-Related Receptors (ERRs) |
| Targets | ERRα, ERRβ and ERRγ |
| Research Category | Nuclear-Receptor and Transcriptional Research |
| Molecular Formula | C18H14N2O2 |
| Molecular Weight | Approximately 290.3 g/mol |
| Amount per Unit | 5mg |
| Units per Bottle | 60 |
| Total Listed Amount | 300mg |
| Intended Use | Laboratory Research Only |
Peptides are composed of amino acids linked by peptide bonds. SLU-PP-332 instead belongs to a different chemical class and is studied as a synthetic small-molecule ligand of nuclear receptors.
Its experimental research context overlaps with certain metabolic and mitochondrial topics discussed in peptide science, but that does not change its chemical classification.
The 5mg × 60 designation means that the bottle contains 60 listed units, with 5mg of SLU-PP-332 per unit, totaling 300mg. The amount and unit count are distinct from any suggested laboratory study design.
SLU-PP-332 is used in research on the three estrogen-related receptor subtypes, ERRα, ERRβ and ERRγ. These nuclear receptors regulate gene-transcription programs associated with cellular energy metabolism.
A pan-ERR agonist refers to a compound with agonist activity across the receptor family. Published pharmacological studies describe SLU-PP-332 as active at all three ERR subtypes, with its strongest reported potency at ERRα.
ERRα is a major topic in nuclear-receptor and mitochondrial research. Its role in transcriptional regulation makes it relevant to studies of genes involved in oxidative phosphorylation, mitochondrial organization and metabolic signaling.
In controlled cell systems, researchers may examine whether activation of ERR-associated pathways changes expression of selected genes. These studies involve gene and protein measurements in defined cell systems.
One approach used in nuclear-receptor pharmacology is a reporter assay, in which activation of a receptor is linked to a measurable signal. Such experiments help characterize the activity and selectivity of an investigational small molecule.
A reporter assay may distinguish compound activity at ERRα from activity at ERRβ and ERRγ. Results depend on the reporter construct, cell system, receptor-expression level and assay controls.
Published studies have examined SLU-PP-332 in cultured muscle-cell systems. Investigated topics include mitochondrial function and cellular respiration under experimental conditions.
This research provides a way to study the relationship between ERR activity and energy-related gene expression.
SLU-PP-332 has also been studied in animal models designed to examine ERR-associated metabolic programs. The early literature includes work on oxidative skeletal-muscle features and ERR-associated gene expression.
Those findings are preclinical observations tied to the specific compound, study model and methods. They do not establish clinical safety or efficacy.
Researchers use chemical probes such as SLU-PP-332 to investigate which molecular structures are associated with stronger or weaker receptor activity. Structure-activity relationship studies compare related compounds while changing features of the chemical scaffold.
More recent research has examined SLU-PP-332 analogs, including receptor selectivity, physicochemical properties and differences in transcriptional responses. Such studies help separate the effect of a chemical modification from an assumption that every ERR agonist behaves identically.
Certificates of Analysis (COAs) are posted on the product page when available. To request documentation for a specific lot, contact the Genoscience team with the lot number.
Keep the bottle sealed in a cool, dry environment protected from direct light and moisture. As a small-molecule research material, SLU-PP-332 should not automatically be given the same storage description as lyophilized peptides.
Handle using standard laboratory protective equipment and facility procedures.
Research Use Only: This product is intended strictly for scientific laboratory research and development.
Not a Peptide: SLU-PP-332 is a synthetic small-molecule compound.
Not for Human or Veterinary Use: Not intended for consumption, administration or veterinary applications.
Not an Approved Medicine: This research material is not marketed as an FDA-approved drug or treatment.
Research Limitations: Results from cultured cells and animal experiments do not establish clinical safety or efficacy.
SLU-PP-332 is a synthetic small molecule studied as an agonist of the estrogen-related receptor family, including ERRα, ERRβ and ERRγ.
No. SLU-PP-332 is a small-molecule research compound rather than an amino-acid peptide. Its research involves nuclear-receptor pharmacology.
The product contains 60 listed units, each with 5mg of SLU-PP-332. The total listed amount is 300mg per bottle.
ERRα, ERRβ and ERRγ are nuclear receptors associated with the regulation of gene expression and cellular metabolism. They are distinct from classical estrogen receptors.
ERR signaling is involved in transcriptional programs related to cellular energy production. Researchers have used SLU-PP-332 to investigate those pathways in experimental systems.
When available, the COA for SLU-PP-332 5mg × 60 can be found on the product page. You may also contact Genoscience to request a COA or ask about documentation availability for a specific lot.
No. Genoscience sells SLU-PP-332 strictly for laboratory research purposes. It is not intended for human or veterinary use.
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