SS-31 30mg Monthly Subscription

Original price was: $270.00.Current price is: $200.00. / month

Subscription of 3 vials for a total of 30mg for only $200.

Compound: SS-31 (Elamipretide / MTP-131)
Concentration: 10mg per vial
Format: Lyophilized Powder
Chemical Classification: Synthetic Mitochondria-Targeting Tetrapeptide / Szeto-Schiller Peptide

Chemical Profile: SS-31 is a synthetic aromatic-cationic tetrapeptide belonging to the Szeto-Schiller peptide family. Structurally, it consists of D-arginine, 2,6-dimethyltyrosine (Dmt), lysine, and C-terminal amidated phenylalanine. SS-31 has been extensively investigated in controlled laboratory systems for its selective interaction with cardiolipin, a phospholipid concentrated within the inner mitochondrial membrane. Experimental studies indicate that this interaction can modify cardiolipin-cytochrome c behavior, mitochondrial electron-transfer kinetics, membrane-associated oxidative processes, and bioenergetic signaling. These characteristics make SS-31 a defined molecular probe for studying mitochondrial membrane chemistry and cardiolipin-dependent processes.

  • Sequence: D-Arg-Dmt-Lys-Phe-NH₂
  • Mechanism: Cardiolipin-binding mitochondrial peptide investigated for modulation of cardiolipin-cytochrome c interactions and electron-transport processes
  • Molecular Weight: ~639.8 g/mol

 

Description

Research Applications & Mechanisms:

  1. Cardiolipin Binding & Inner Mitochondrial Membrane Research
    SS-31 has been investigated for its selective interaction with cardiolipin-containing membranes. Experimental studies using liposomes, bicelles, and isolated mitochondrial systems have demonstrated interactions between SS-31 and cardiolipin, providing researchers with a molecular tool for examining membrane organization, lipid-peptide interactions, and cardiolipin-dependent biochemical processes.
  2. Cytochrome c / Cardiolipin Complex Research
    Cardiolipin can interact with cytochrome c and alter its molecular behavior within mitochondrial membranes. SS-31 has been studied for its ability to modify this cardiolipin-cytochrome c interaction, including effects on cytochrome c peroxidase activity and preservation of its electron-carrier function. These properties support mechanistic studies of mitochondrial electron-transfer chemistry and membrane-associated protein-lipid interactions.
  3. Electron Transport & Mitochondrial Respiration
    Laboratory studies using isolated mitochondrial preparations have examined SS-31 in relation to electron flux and oxygen-consumption measurements. Experimental findings have reported changes in mitochondrial respiration and electron-transfer efficiency, making the peptide useful for assays investigating the relationship between cardiolipin organization, cytochrome c activity, and respiratory-chain function.
  4. Reactive Oxygen Species & Oxidative Signaling Models
    SS-31 has been studied in experimental systems measuring mitochondrial reactive oxygen species, hydrogen peroxide production, and cardiolipin-associated oxidative processes. Rather than functioning simply as a nonspecific antioxidant reagent, SS-31 provides a framework for examining how mitochondrial membrane interactions can influence localized oxidative chemistry and electron leakage under defined laboratory conditions.
  5. Mitochondrial Bioenergetics & ATP-Associated Assays
    The relationship between inner-membrane organization and oxidative phosphorylation makes SS-31 relevant to mitochondrial bioenergetics research. Isolated mitochondrial studies have examined oxygen consumption, respiratory-chain activity, and ATP-associated measurements following SS-31 exposure, allowing researchers to investigate how cardiolipin-dependent membrane processes influence measurable bioenergetic endpoints.

Important Notices:

  • Research Use Only: This Genoscience product is sold strictly for scientific research, analytical testing, and laboratory development purposes. It is not intended or offered for human or animal use.
  • Handling: The product is supplied as a lyophilized powder and should be handled using appropriate laboratory protocols for peptide stability, solubility, contamination control, and analytical preparation.
  • Visuals: Vial appearance and cap color may vary from product photos; the label quantity refers to the total active content inside the vial.

Important Legal & Safety Notice: This Genoscience product is intended exclusively for in-vitro research and analytical use. It is not intended for human or animal consumption or administration. Researchers are solely responsible for ensuring that handling, reconstitution, storage, and experimental protocols comply with all applicable institutional, ethical, and legal requirements.

 

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