TB-500 2mg

One vial 2 mg was $45 now $30

Compound: TB-500 (Thymosin Beta-4-Related Research Peptide)

Amount: 2mg per vial

Format: Lyophilized Powder

Chemical Classification: Synthetic Thymosin Beta-4-Related Peptide Material

Research Category: Actin, Cytoskeleton and Cell-Migration Research

Chemical Profile: TB-500 is a research product name associated with the thymosin beta-4 peptide family. Scientific literature on thymosin beta-4 examines interactions with monomeric actin and processes involved in cytoskeletal regulation and cellular movement. The full-length 43-residue peptide and shorter thymosin beta-4-derived fragments are different molecular materials, so studies of one form should not automatically be applied to another.

Research Use Only. Not for human or veterinary use.

Monthly subscription eight vials of 2 mg for a total of 16 mg was $170 now $110

TB-500 Research Overview

TB-500 is a product name used in the thymosin beta-4 research category. Thymosin beta-4 (Tβ4) is a naturally occurring 43-amino-acid peptide associated with binding monomeric, or G-actin, within cells.

The terms TB-500 and thymosin beta-4 are sometimes used interchangeably in product listings. However, the TB-500 name is also used for peptide fragments derived from thymosin beta-4. A fragment and a full-length peptide do not have the same sequence or molecular mass.

Refer to the lot Certificate of Analysis for the identity of the supplied material.

Technical Specifications

SpecificationDetails
Product NameTB-500
Research ClassificationThymosin Beta-4-Related Peptide Material
Associated Parent PeptideThymosin Beta-4 (Tβ4)
Parent Peptide Length43 Amino Acids
Key Parent-Peptide Research TopicMonomeric Actin (G-Actin) Interaction
FormLyophilized Powder
Amount2mg per Vial
Intended UseLaboratory Research Only

Thymosin Beta-4 and Its Fragments

Full-length thymosin beta-4 is associated with the actin-binding sequence region around residues 17–23, commonly discussed as the LKKTETQ motif.

A peptide consisting of that shorter fragment is chemically distinct from the full 43-residue thymosin beta-4 peptide. They should not be assigned the same molecular specifications by default.

Why Molecular Identity Matters

The 43-residue parent peptide and shorter fragments differ in sequence length, molecular mass and potentially experimental behavior. Findings based on full-length thymosin beta-4 describe that specific molecular preparation.

This distinction is especially relevant for comparing published literature with commercially named TB-500 materials.

1. Thymosin Beta-4 and G-Actin Research

Thymosin beta-4 is widely discussed in research on actin-binding proteins and peptides. Actin exists in monomeric (G-actin) and filamentous (F-actin) forms, which are important to cell shape and movement.

Published studies of full-length thymosin beta-4 examine its interactions with G-actin and the balance between soluble and polymerized actin. These are molecular properties of the studied peptide, not proof of an effect for every product named TB-500.

2. Actin Filament Dynamics

Actin filaments are dynamic cytoskeletal structures. Their assembly and disassembly are studied in relation to cellular organization, migration and intracellular mechanics.

Research on thymosin beta-4 provides biochemical context for understanding proteins and peptides that influence actin availability. Such experiments may use purified proteins, cell cultures or other controlled model systems.

3. The LKKTETQ Sequence Region

A research topic in thymosin beta-4 studies is the sequence region containing the LKKTETQ motif, associated with actin interactions.

Short peptides derived from this region can be investigated independently from the full-length molecule. Researchers studying such fragments distinguish their findings from data obtained with a 43-residue parent peptide.

4. Cell Migration and Cytoskeletal Models

Cell migration involves coordinated rearrangement of the cytoskeleton. Thymosin beta-4-related literature includes cell-culture and preclinical models that investigate how actin-associated signaling participates in cellular movement.

These studies describe molecular and cellular mechanisms. They do not establish that a commercially named research material provides a clinical result.

5. Comparative Peptide Identity Studies

Comparisons between a parent peptide and a derived fragment are a common part of peptide science. Structural differences may alter molecular interactions, experimental readouts and analytical characteristics.

In this area, the distinction between thymosin beta-4 and a possible fragment is essential because reported experiments can involve different chemical entities despite similar terminology.

6. TB-500 Versus BPC-157

TB-500-related materials and BPC-157 belong to separate peptide research categories. BPC-157 is a 15-amino-acid peptide with its own defined sequence, whereas thymosin beta-4 research focuses on a different peptide family and actin-related biology.

They are sometimes listed together in multi-component research blends, but this does not mean they share the same molecular mechanism or establish a combined effect.

Selected Scientific Reference

  • Ying et al. (2023). Thymosin β4 and Actin: Binding Modes, Biological Functions and Clinical Applications. PubMed

Quality & Documentation

Certificates of Analysis (COAs) are posted on the product page when available. To request documentation for a specific lot, contact the Genoscience team with the lot number.

Storage & Handling

Keep unopened lyophilized research material at −20 °C, dry and protected from light and moisture. Allow the sealed vial to reach room temperature before opening to reduce condensation.

Use laboratory protective equipment and established research-facility procedures.

Research Use Only: This product is intended strictly for laboratory research and development.

Not for Human or Veterinary Use: Not intended for human consumption, administration or veterinary applications.

Not an Approved Medicine: This research material is not marketed as an FDA-approved drug or treatment.

Research Limitations: Literature describing full-length thymosin beta-4 or individual fragments may not apply to every material named TB-500. Preclinical findings do not establish clinical safety or efficacy for this product.

What is TB-500?

TB-500 is a product name associated with thymosin beta-4-related peptide research, including studies involving actin and cytoskeletal regulation.

Is TB-500 identical to thymosin beta-4?

Not necessarily. The TB-500 name is used for different thymosin beta-4-related preparations. A full-length peptide and a short fragment are chemically different materials.

What is thymosin beta-4?

Thymosin beta-4 is a 43-amino-acid peptide studied for its interaction with monomeric actin and its role in cytoskeletal processes.

How does TB-500 differ from BPC-157?

BPC-157 is a distinct 15-residue peptide. TB-500 refers to a thymosin beta-4-related research category and is associated with a different molecular background.

What amount does a TB-500 vial contain?

Genoscience lists TB-500 2mg as a lyophilized research material containing 2mg per vial.

Where can I find the Certificate of Analysis (COA) for TB-500 2mg?

When available, the COA for TB-500 2mg can be found on the product page. You may also contact Genoscience to request a COA or ask about documentation availability for a specific lot.

Is TB-500 2mg intended for human use?

No. Genoscience sells TB-500 2mg strictly for laboratory research. It is not intended for human or veterinary use.

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